(2R)-Amino-3-(5-bromothiophen-2-yl)propionic acid - Names and Identifiers
(2R)-Amino-3-(5-bromothiophen-2-yl)propionic acid - Physico-chemical Properties
Molecular Formula | C7H8BrNO2S
|
Molar Mass | 250.11 |
Density | 1.747±0.06 g/cm3(Predicted) |
Boling Point | 368.5±42.0 °C(Predicted) |
Flash Point | 159.828°C |
Vapor Presure | 0mmHg at 25°C |
pKa | 2.09±0.10(Predicted) |
Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Refractive Index | 1.631 |
(2R)-Amino-3-(5-bromothiophen-2-yl)propionic acid - Introduction
(2S)-2-amino-2-(5-bromo-2-thienyl)propanoic acid is an organic compound with the chemical formula C7H9BrNO2S. The following is a description of its nature, use, preparation and safety information:
Nature:
-Appearance: White or off-white solid.
-Melting point: about 160-165°C.
-Solubility: Partially soluble in water, soluble in acidic solutions and organic solvents, such as methanol, dimethyl ether and chloroform.
Use:
- (2S)-2-amino-2-(5-bromo-2-thienyl)propanoic acid is an important organic synthesis intermediate. It can be used to synthesize drugs, pesticides or other organic compounds.
-Due to the special properties of its thiophene ring structure,(2S)-2-amino-2-(5-bromo-2-thienyl)propanoic acid is also commonly used in the research and development of organic optoelectronic materials.
Method:
The preparation method of
- (2S)-2-amino-2-(5-bromo-2-thienyl)propanoic acid generally involves the empirical synthesis of thienthione.
-A common preparation method is to first react 2-bromothiophene and dimethyl sulfoxide through sodium sulfide to obtain 2-thiophenone. Then, 2-thienethione and glycine were subjected to an acid chloride substitution reaction to finally obtain the target product.
Safety Information:
-Due to the presence of the bromine substituent of the compound,(2S)-2-amino-2-(5-bromo-2-thienyl)propanoic acid may have certain toxicity and irritation.
-During operation, it is necessary to wear appropriate personal protective equipment, such as protective glasses, protective gloves and laboratory coats, to avoid contact with skin and eyes.
-During handling and storage, care should be taken to avoid contact with fire, heat and strong oxidants to prevent accidents.
-Detailed safety information and operating precautions should be referenced in accordance with the safety data sheet provided by the manufacturer.
Last Update:2024-04-09 21:04:16